October 25, 2021 – 790th Meeting – 5pm

Georgiana Purdy, Ph.D.
Professor, Department of Molecular Microbiology and Immunology
School of Medicine
Oregon Health & Sciences University

Laboratory of Georgiana Purdy Ph.D, OHSU

“The Big Ball of Wax: The Role of MmpL Transporters in Mycobacterium tuberculosis Cell Wall Biosynthesis, Virulence and Non-replicating Persistance”

TB is a leading infectious disease that causes death despite the availability of anti-tubercular drugs. The MmpL transporters make a crucial contribution to mycobacterial physiology and pathogenesis by exporting cell wall lipids to the mycobacterial outer membrane. This talk will describe the role of the essential MmpL3 transporter in cell wall biogenesis and show the contribution of MmpL11 to virulence and non-replicating persistence.

Zoom information to be emailed to Branch members. Non-members can live stream the meeting on our YouTube channel.